Description

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Platelet-rich plasma, popularly called PRP, is a fraction of autologous blood plasma containing concentrated platelets. PRP has gained increasing interest for its dramatic benefits in the treatment of musculoskeletal injuries, especially for some refractory diseases such as pressure ulcers, diabetic foot ulcers, tendinopathy, or osteoarthritis. High concentrations of autologous growth factors released from activated PRP compensate for the deficiency of growth factors in these refractory diseases. In addition to the advantages of providing high concentrations of growth factors, PRP therapy also has the advantages of being safe, simple, and effective in treating a wide range of acute and chronic musculoskeletal diseases. To date, PRP has been used in a variety of clinical practices for tissue repair and regeneration, pain relief, and to delay or even avoid the choice of surgery. This book covers a variety of topics from basic science to clinical applications and is suitable for both freshmen and experienced physicians interested in PRP therapy.

About the Author

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Dr. Xie is an experienced orthopaedic surgeon in Shanghai Sixth People’s Hospital affiliated to Shanghai Jiao Tong University. He obtained M.D. in Tongji University in 2004, and Ph.D. in Shanghai Jiao Tong University in 2013 for the years of research focusing on platelet-rich plasma (PRP) in treatment of cartilage repair. With the sponsorship from China government, he conducted an international collaborative program from 2011 to 2013 in University of Pittsburgh in Pittsburgh, PA, United States. Dr. Yuan is an associate professor in the department of orthopaedic surgery at Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University. He got M.D. in 2001 and Ph.D in 2015. He currently serves as the Vice-Chairman of committee of regenerative medicine and rehabilitation branch of Chinese Association of Rehabilitation Medicine (CARM). As one of the first medical scientists to study platelet-rich plasma (PRP), Dr. Yuan has been studying the mechanism and efficacy of PRP in the treatment of bone defect, cutaneous wounds, osteoarthritis, and ligament injuries, et al for about 20 years. Shumin Zhou, assistant professor of Shanghai Jiaotong University Affinity Sixth People Hospital, is mainly interested in the pathology and repair of bone. Dr. Zhou got his doctor degree in Wuhan University, majored in molecular virology, worked in Shanghai Centre for System Biomedical in Shanghai Jiaotong University as a post-doctor, and majored in proteomics research.